The building was completed in June 1839, and in August Edward & Elizabeth ORME were appointed as the first School Master and Mistress at £90 pa (joint salary). In 1841, they were living at Bath Villas, Aigburth with their six children. They were still in Aigburth in 1851. The school was well established by the 1840s with a committee chaired by the vicar. It was deemed necessary to expand, because: 'An Infant school has now become indispensible on account of the late rapid increase of the Cottage population...'

Early Regulations for St. Anne’s School, Aigburth Vale.

The School opened in 1839 for children above five years of age. Hours were 9-12 & 2-5.

There were two weeks for summer holiday and one at Christmas.

An adjacent plot of land was acquired and the building complete by June 1855. In 1882, the girls’ school was extended. This was a large school; in 1900, average attendance was about 450 pupils. However, by the 1930s, new Local Authority schools in South Liverpool (notably Sudley, I would imagine) meant that numbers were declining. The girls’ school was closed after air raid damage in 1941. School continued as Mixed Infants until 1963 when the school closed and the buildings were demolished.